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The potential unwanted effects of anything consumed should taken into consideration. If the identification of active ingredients is not possible, then whole herbal medicine can be considered as one active ingredient 3. World Health Organization (WHO) defines herbal medicines as “herbs, herbal materials, herbal preparations and finished herbal products that contain parts of plants, other plant materials, or combinations as active ingredients.” WHO also clarifies “active ingredients” as “the ingredients of herbal medicines with therapeutic activity where the active ingredients have been identified, and if adequate analytical methods are available, the medicinal preparation should be standardized to contain a defined amount of the active ingredients”. With the use of alkaloids and glycosides, the compounds with a pharmacological activity have been known and their toxic potential has been also revealed 2.Īctually many pharmacological agents used today have their origins in plant-based compounds such as atropine (Atropa belladonna), ephedrine (Ephedra spp.), morphine and codeine (Papaver somniferum), cocaine (Erythroxylum coca), pilocarpine (Pilocarpus jaborandi Holmes), and quinine (Cinchona cordifolia Mutis ex Humb) 2. With the solvent extraction technique, the compounds of plants with pharmacological activity became available. Therefore, the isolation of active principles in plants and determining its amount is of great importance. This risk is even higher with plants as they contain variable mixture of compounds. Drugs have adverse effects due to interaction with other components. They are either produced or manufactured from roots, leaves, bark, buds, berries or seeds of the plants 1.įor a drug or a herbal product to exert a response, it must at least interact with a component of the organism at molecular level. Over the centuries, plants are being relied on by humans not only for feeding and clothing but also for medical needs. Bu derlemenin amacı, hamilelikte en sık kullanılan, bitkisel çay olarak tüketilen bitkilerin olası toksik etkilerini özetleyerek kullanımında dikkatli olunması gerektiğinin önemini vurgulamaktır. Hamilelikte en sık kullanılan bitkisel preparatlar, genellikle en düşük konsantrasyonlara sahip olan ve en az miktarda bileşik içeren çaylar veya infüzyonlardır (kurutulmuş otların sıcak su özleri). Bir bitkisel ürünün yanıt oluşturabilmesi için, bir ilacın yanıt oluşturması gibi, ürünün organizmanın bir bileşeni ile moleküler seviyede etkileşime girmesi gereklidir. Herhangi bir maddenin özellikle de hamilelik döneminde olası istenmeyen etkileri önemlidir, çünkü hızlı büyüyen fetüsün hücresel gelişimi ve hücre bölünmesi etkilenmeye açıktır. “Doğal olan güvenlidir” inancıyla, bitkiler ve bitkisel ürünlerinin kullanımı dünya genelinde popüler hale gelmiştir ve hamilelik dönemi dahil sıklıkla kullanılmaktadır.
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Hamilelikte bitkisel ürün kullanımın prevalansı coğrafya ve sosyo-kültürel faktörlere bağlı olarak, değişmektedir. The purpose of this review is to summarize the herbs that are most commonly used as “herbal teas” during pregnancy and their potential toxic effects to highlight the importance of being cautious about their use.
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Herbal preparations most commonly used during pregnancy were teas or infusions (hot-water extracts of dried herbs) which usually have the lowest concentrations and contain the least amount of compounds. As with medicines, herbal products must at least interact with a component of the organism at the molecular level in order to exert a response. The potential unwanted effects of any substance is more important during pregnancy period, because cellular development and division of the rapidly growing fetus is vulnerable to these adverse effects. With the belief of “being natural is safe”, use of herbs and herbal products has become popular worldwide and used more frequently including period of pregnancy. The prevalence of herbal medicine use during pregnancy varies depending upon the geographical location and socio-cultural factors.